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Journal articleAlexander JL, Mullish BH, 2020,
A Guide to the Gut Microbiome and its Relevance to Critical Care
, British Journal of Nursing, Vol: 29, Pages: 1106-1112, ISSN: 0966-0461<jats:p> Although it is well-established that particular bacteria may cause gastroenteritis and other infections when present in the gut, it is only recently that scientists have made significant inroads into understanding the huge number of other bacteria and additional microbes that live within the gastrointestinal tract, referred to as the gut microbiome. In particular, it is now recognised that bacteria within the gut microbiome have a wide variety of roles in maintaining different aspects of human health, and that disturbances of these bacteria may potentially cause or contribute to a number of different medical conditions, including particular infections, certain cancers, and chronic conditions, including inflammatory bowel disease. Moreover, there is increasing awareness that these bacteria help determine how the body responds to medication, including antibiotics and chemotherapy. There has been growing interest in different approaches to alter the gut microbiome as a novel approach to medical therapy. This article provides an overview of the importance of the gut microbiome, with a particular focus on critical care. </jats:p>
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Conference paperAllegretti JR, Kelly C, Grinspan AM, et al., 2020,
S0650 Fecal Microbiota Transplantation Decolonizes C. difficile in Patients With Inflammatory Bowel Disease and Concomitant C. difficile Infection
, Publisher: Ovid Technologies (Wolters Kluwer Health), Pages: S326-S326, ISSN: 0002-9270 -
Journal articleIaniro G, Mullish BH, Kelly CR, et al., 2020,
Reorganisation of faecal microbiota transplant services during the COVID-19 pandemic
, Gut, Vol: 69, Pages: 1555-1563, ISSN: 0017-5749<jats:p>The COVID-19 pandemic has led to an exponential increase in SARS-CoV-2 infections and associated deaths, and represents a significant challenge to healthcare professionals and facilities. Individual countries have taken several prevention and containment actions to control the spread of infection, including measures to guarantee safety of both healthcare professionals and patients who are at increased risk of infection from COVID-19. Faecal microbiota transplantation (FMT) has a well-established role in the treatment of <jats:italic>Clostridioides difficile</jats:italic> infection. In the time of the pandemic, FMT centres and stool banks are required to adopt a workflow that continues to ensure reliable patient access to FMT while maintaining safety and quality of procedures. In this position paper, based on the best available evidence, worldwide FMT experts provide guidance on issues relating to the impact of COVID-19 on FMT, including patient selection, donor recruitment and selection, stool manufacturing, FMT procedures, patient follow-up and research activities.</jats:p>
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Journal articleSegal JP, Mullish BH, Quraishi MN, et al., 2020,
Letter: faecal microbiota transplantation for IBS
, Alimentary Pharmacology & Therapeutics, Vol: 52, Pages: 556-557, ISSN: 0269-2813 -
Journal articleIaniro G, Segal JP, Mullish BH, et al., 2020,
Fecal microbiota transplantation in gastrointestinal and extraintestinal disorders
, Future Microbiology, ISSN: 1746-0913 -
Journal articleMcIlroy JR, Mullish BH, Goldenberg SD, et al., 2020,
Intestinal microbiome transfer, a novel therapeutic strategy for COVID-19 induced hyperinflammation?
, Clinical Immunology, ISSN: 1521-6616 -
Journal articleVieira-Silva S, Falony G, Belda E, et al., 2020,
Statin therapy is associated with lower prevalence of gut microbiota dysbiosis
, NATURE, Vol: 581, Pages: 310-+, ISSN: 0028-0836- Author Web Link
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Journal articleBlanco JM, Liu Z, Selvarajah U, et al., 2020,
Sa1923 identification of new associations between psoriatic arthritis and the gut microbiota, a phenomic study
, Gastroenterology, Vol: 158, Pages: S-481, ISSN: 0016-5085 -
Journal articleAllegretti JR, Kassam Z, Hurtado J, et al., 2020,
Tu1909 IMPACT OF FECAL MICROBIOTA TRANSPLANTATION ON PREVENTION OF METABOLIC SYNDROME AMONG PATIENTS WITH OBESITY
, Gastroenterology, Vol: 158, ISSN: 0016-5085 -
Conference paperGhani R, Mullish BH, McDonald JA, et al., 2020,
1144 FECAL MICROBIOTA TRANSPLANT FOR MULTI-DRUG RESISTANT ORGANISMS: IMPROVED CLINICAL OUTCOMES BEYOND INTESTINAL DECOLONISATION
, Publisher: Elsevier BV, ISSN: 0016-5085
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