Research

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Synthetic Biology underpins advances in the bioeconomy

Biological systems - including the simplest cells - exhibit a broad range of functions to thrive in their environment. Research in the Imperial College Centre for Synthetic Biology is focused on the possibility of engineering the underlying biochemical processes to solve many of the challenges facing society, from healthcare to sustainable energy. In particular, we model, analyse, design and build biological and biochemical systems in living cells and/or in cell extracts, both exploring and enhancing the engineering potential of biology. 

As part of our research we develop novel methods to accelerate the celebrated Design-Build-Test-Learn synthetic biology cycle. As such research in the Centre for Synthetic Biology highly multi- and interdisciplinary covering computational modelling and machine learning approaches; automated platform development and genetic circuit engineering ; multi-cellular and multi-organismal interactions, including gene drive and genome engineering; metabolic engineering; in vitro/cell-free synthetic biology; engineered phages and directed evolution; and biomimetics, biomaterials and biological engineering.

Publications

Citation

BibTex format

@article{de:2018:10.15252/embr.201745658,
author = {de, Lorenzo V and Prather, KL and Chen, G-Q and O'Day, E and von, Kameke C and Oyarzún, DA and Hosta-Rigau, L and Alsafar, H and Cao, C and Ji, W and Okano, H and Roberts, RJ and Ronaghi, M and Yeung, K and Zhang, F and Lee, SY},
doi = {10.15252/embr.201745658},
journal = {EMBO Reports},
title = {The power of synthetic biology for bioproduction, remediation and pollution control},
url = {http://dx.doi.org/10.15252/embr.201745658},
volume = {19},
year = {2018}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AU  - de,Lorenzo V
AU  - Prather,KL
AU  - Chen,G-Q
AU  - O'Day,E
AU  - von,Kameke C
AU  - Oyarzún,DA
AU  - Hosta-Rigau,L
AU  - Alsafar,H
AU  - Cao,C
AU  - Ji,W
AU  - Okano,H
AU  - Roberts,RJ
AU  - Ronaghi,M
AU  - Yeung,K
AU  - Zhang,F
AU  - Lee,SY
DO  - 10.15252/embr.201745658
PY  - 2018///
SN  - 1469-221X
TI  - The power of synthetic biology for bioproduction, remediation and pollution control
T2  - EMBO Reports
UR  - http://dx.doi.org/10.15252/embr.201745658
UR  - https://www.ncbi.nlm.nih.gov/pubmed/29581172
UR  - http://hdl.handle.net/10044/1/58688
VL  - 19
ER  -
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