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News archive

  • news

08 July 2024

Imperial and Crick cancer drug spinout raises £90m to begin clinical development

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28 June 2024

Proximity-based labelling for proteomic mapping

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15 May 2024

ZDHHC20 promotes cancer immune evasion, a potential target in pancreatic cancer

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04 March 2024

Nature Reviews Cancer: Protein Lipidation

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27 November 2023

Unraveling the Secrets of Zombie cells

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18 November 2023

Molecular causes of rare neurological condition in children revealed

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20 February 2023

UV-light activated probe finds new interactions in living cells

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20 October 2022

Blocking poxvirus infectiousness with NMT inhibitors

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21 December 2021

Structure, mechanism, and inhibition of Hedgehog Acyltransferase

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23 August 2021

Targeting methionine aminopeptidase 2 in cancer, obesity and autoimmunity

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27 April 2021

Identification of a small-molecule inhibitor binding site in HHAT

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31 March 2021

N-myristoyltransferase inhibition selectively kills MYC-deregulated cancer cells

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04 February 2021

Deconvoluting protein lipidation using chemical proteomics

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11 August 2020

Profiling of modified proteins identifies a component of parasitic invasion

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13 July 2020

Structure-activity relationships for therapeutics of neglected tropical disease

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29 May 2020

N-myristoyltransferase inhibitors against wheat pathogen Zymoseptoria tritici

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14 April 2020

New research comparing human and bat immune response to viral infections

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03 April 2020

Re-evaluating the mechanism of action of DUB inhibitors

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25 March 2020

Faecal neutrophil elastase-antiprotease and its activity on colitis severity

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09 March 2020

High resolution snapshots of NMT1 in action

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18 April 2019

The good, the bad and the ugly: chemical probes for human NMT

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19 September 2018

Parasites, photocrosslinking lipids, and activity-based probes

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Research

  • Chemical biology and drug discovery
  • Targeted and proximity-induced pharmacology
  • Proteomics and post-translational modification (PTM)

Contact

Prof. Ed Tate
GSK Chair in Chemical Biology
Department of Chemistry
Molecular Sciences Research Hub, White City Campus,
82 Wood Lane, London, W12 0BZ

e.tate@imperial.ac.uk
Tel: +44 (0)20 759 + ext 43752 or 45821

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