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Journal articleJiang N, Wang Y, Yin Y-X, et al., 2018,
bFGF and Poly-RGD Cooperatively Establish Biointerface for Stem Cell Adhesion, Proliferation, and Differentiation
, ADVANCED MATERIALS INTERFACES, Vol: 5, ISSN: 2196-7350 -
Journal articleElsherif M, Hassan MU, Yetisen AK, et al., 2018,
Glucose sensing with phenylboronic acid functionalized hydrogel-based optical diffusers
, ACS Nano, Vol: 12, Pages: 2283-2291, ISSN: 1936-0851Phenylboronic acids have emerged as synthetic receptors that can reversibly bind to cis-diols of glucose molecules. The incorporation of phenylboronic acids in hydrogels offers exclusive attributes; for example, the binding process with glucose induces Donnan osmotic pressure resulting in volumetric changes in the matrix. However, their practical applications are hindered because of complex readout approaches and their time-consuming fabrication processes. Here, we demonstrate a microimprinting method to fabricate densely packed concavities in phenylboronic acid functionalized hydrogel films. A microengineered optical diffuser structure was imprinted on a phenylboronic acid based cis-diol recognizing motif prepositioned in a hydrogel film. The diffuser structure engineered on the hydrogel was based on laser-inscribed arrays of imperfect microlenses that focused the incoming light at different focal lengths and direction resulting in a diffused profile of light in transmission and reflection readout modes. The signature of the dimensional modulation was detected in terms of changing focal lengths of the microlenses due to the volumetric expansion of the hydrogel that altered the diffusion spectra and transmitted beam profile. The transmitted optical light spread and intensity through the sensor was measured to determine variation in glucose concentrations at physiological conditions. The sensor was integrated in a contact lens and placed over an artificial eye. Artificial stimulation of variation in glucose concentration allowed quantitative measurements using a smartphone’s photodiode. A smartphone app was utilized to convert the received light intensity to quantitative glucose concentration values. The developed sensing platform offers low cost, rapid fabrication, and easy detection scheme as compared to other optical sensing counterparts. The presented detection scheme may have applications in wearable real-time biomarker monitoring devices at point-of-care
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Journal articleKim H, Beack S, Han S, et al., 2018,
Multifunctional Photonic Nanomaterials for Diagnostic, Therapeutic, and Theranostic Applications
, ADVANCED MATERIALS, Vol: 30, ISSN: 0935-9648 -
Journal articleZhang Z, Dou Q, Gao H, et al., 2018,
30 s Response Time of K+ Ion-Selective Hydrogels Functionalized with 18-Crown-6 Ether Based on QCM Sensor
, ADVANCED HEALTHCARE MATERIALS, Vol: 7, ISSN: 2192-2640 -
Journal articleGeng W, Wang L, Jiang N, et al., 2018,
Single cells in nanoshells for the functionalization of living cells
, NANOSCALE, Vol: 10, Pages: 3112-3129, ISSN: 2040-3364 -
Journal articleHassaan MU, Liu Y-C, ul Hasan K, et al., 2018,
Highly Efficient Energy Transfer in Light Emissive Poly(9,9-dioctylfluorene) and Poly(p-phenylenevinylene) Blend System
, ACS PHOTONICS, Vol: 5, Pages: 607-613, ISSN: 2330-4022 -
Journal articleHassan MU, Liu Y-C, Yetisen AK, et al., 2018,
Energy Landscape of Vertically Anisotropic Polymer Blend Films toward Highly Efficient Polymer Light-Emitting Diodes (PLEDs)
, ADVANCED FUNCTIONAL MATERIALS, Vol: 28, ISSN: 1616-301X -
Journal articleJiang N, Ahmed R, Rifat AA, et al., 2018,
Functionalized Flexible Soft Polymer Optical Fibers for Laser Photomedicine
, ADVANCED OPTICAL MATERIALS, Vol: 6, ISSN: 2195-1071 -
Journal articleKhalid MW, Ahmed R, Yetisen AK, et al., 2018,
Flexible corner cube retroreflector array for temperature and strain sensing
, RSC ADVANCES, Vol: 8, Pages: 7588-7598, ISSN: 2046-2069- Author Web Link
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- Citations: 8
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Journal articleAlQattan B, Benton D, Yetisen AK, et al., 2017,
Laser nanopatterning of colored ink thin films for photonic devices
, ACS Applied Materials and Interfaces, Vol: 9, Pages: 39641-39649, ISSN: 1944-8244Nanofabrication through conventional methods such as electron beam writing and photolithography is time-consuming, high cost, complex, and limited in terms of the materials which can be processed. Here, we present the development of a nanosecond Nd:YAG laser (532 nm, 220 mJ) in holographic Denisyuk reflection mode method for creating ablative nanopatterns from thin films of four ink colors (black, red, blue, and brown). We establish the use of ink as a recording medium in different colors and absorption ranges to rapidly produce optical nanostructures in 1D geometries. The gratings produced with four different types of ink had the same periodicity (840 nm); however, they produce distant wavelength dependent diffraction responses to monochromatic and broadband light. The nanostructures of gratings consisting of blue and red inks displayed high diffraction efficiency of certain wavelengths while the black and brown ink based gratings diffracted broadband light. These gratings have high potential to be used as low-cost photonic structures in wavelength-dependent optical filters. We anticipate that the rapid production of gratings based on different ink formulations can enable optics applications such as holographic displays in data storage, light trapping, security systems, and sensors.
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Journal articleDeng S, Jwad T, Li C, et al., 2017,
Carbon Nanotube Array Based Binary Gabor Zone Plate Lenses
, SCIENTIFIC REPORTS, Vol: 7, ISSN: 2045-2322- Author Web Link
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- Citations: 2
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Journal articleAlqurashi T, Montelongo Y, Penchev P, et al., 2017,
Correction: Femtosecond laser ablation of transparent microphotonic devices and computer-generated holograms
, Nanoscale, Vol: 9, Pages: 15159-15159, ISSN: 2040-3364 -
Journal articleRashid I, Butt H, Yetisen AK, et al., 2017,
Wavelength-Selective Diffraction from Silica Thin-Film Gratings
, ACS PHOTONICS, Vol: 4, Pages: 2402-2409, ISSN: 2330-4022 -
Journal articleAlqurashi T, Montelongo Y, Penchev P, et al., 2017,
Femtosecond laser ablation of transparent microphotonic devices and computer-generated holograms
, NANOSCALE, Vol: 9, Pages: 13808-13819, ISSN: 2040-3364 -
Conference paperVega K, Jiang N, Liu X, et al., 2017,
The Dermal Abyss: Interfacing with the Skin by Tattooing Biosensors
, ACM International Joint Conference on Pervasive and Ubiquitous Computing (UBICOMP) / ACM International Symposium on Wearable Computers (ISWC), Publisher: ASSOC COMPUTING MACHINERY, Pages: 138-145 -
Journal articleKhalid MW, Ahmed R, Yetisen AK, et al., 2017,
Holographic Writing of Ink-Based Phase Conjugate Nanostructures via Laser Ablation
, SCIENTIFIC REPORTS, Vol: 7, ISSN: 2045-2322- Author Web Link
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- Citations: 11
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Journal articleDou Q, Hu D, Gao H, et al., 2017,
High performance boronic acid-containing hydrogel for biocompatible continuous glucose monitoring
, RSC Advances: an international journal to further the chemical sciences, Vol: 7, Pages: 41384-41390, ISSN: 2046-2069Rapid and robust hydrogels are essential in realizing continuous glucose monitoring in diabetes monitoring. However, existing hydrogels are limited in satisfying all of the sensory requirements such as detection range, response time, recoverability and biocompatibility. Here, we have developed a surface-initiated polymerization method to chemically immobilize a nano-boronic acid-hydrogel membrane onto a quartz crystal, then used a quartz crystal microbalance (QCM) to achieve real-time monitoring of glucose. The experimental results show that this hydrogel possesses enhanced binding properties to glucose under physiological conditions (pH 7.0–7.5) and blood glucose concentration (BGC) (1.1–33.3 mM). Moreover, our hydrogel displayed a rapid response time (∼100 s) to glucose, high biocompatibility in vivo through an animal model. The hydrogel has a great potential as a sensitive glucose probe for implantable continuous glucose sensors.
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Journal articleTamayol A, Najafabadi AH, Mostafalu P, et al., 2017,
Biodegradable elastic nanofibrous platforms with integrated flexible heaters for on-demand drug delivery
, SCIENTIFIC REPORTS, Vol: 7, ISSN: 2045-2322- Author Web Link
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- Citations: 70
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Journal articleBentaleb EM, El Messaoudi MD, Abid M, et al., 2017,
Plasmid-based high-resolution melting analysis for accurate detection of rpoB mutations in Mycobacterium tuberculosis isolates from Moroccan patients
, BMC INFECTIOUS DISEASES, Vol: 17, ISSN: 1471-2334- Author Web Link
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- Citations: 3
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