The Centre of Neuroinflammation and Neurodegeneration (NN) investigates mechanisms of neurodegeneration and neuroinflammation common to many neurological disorders including Alzheimer’s disease and other dementias, Parkinson’s disease and Parkinson’s Plus syndromes, Motor Neuron diseases, Huntington’s disease, and Multiple Sclerosis. Several clinical and preclinical studies are currently ongoing with the aim to improve our understanding of these diseases and develop and test novel therapeutic strategies. The Centre fosters close collaboration between both clinicians and basic science researchers from a wide range of scientific backgrounds to facilitate effective translational research.

The Centre is home to The Multiple Sclerosis and Parkinson’s Tissue Bank, a national collection of central nervous system (CNS) tissue samples donated by individuals with multiple sclerosis (MS), Parkinson’s disease and related neuroinflammatory and neurodegenerative conditions. The Tissue Bank’s mission is to facilitate these discoveries by making well-characterised human material of the highest quality readily available to the research community engaged in studies aimed at discovering the cause and better treatments for multiple sclerosis and Parkinson’s disease.

Our academic members of staff are major contributors to the Undergraduate and Postgraduate teaching programmes in Neuroscience, Neurology and Molecular Biology at Imperial College London. We also offer opportunities for continuous personal development in academia.